Memorial Sloan Kettering Cancer Center
NCIS Grant

NANETS congratulates Etay Ziv, MD, PhD of Memorial Sloan Kettering Cancer Center as the 2017 NANETS Clinical Investigator Scholarship recipient. The NCIS award focuses on supporting a clinical project as well as the investigator's potential to make future clinical contributions to the neuroendocrine tumor field. This award is in honor of Edda Gomez-Panzani, MD for her dedication and work on behalf of patients living with neuroendocrine tumors.

The 2017 recipient, Dr. Etay Ziv, seeks to improve the outcome of patients undergoing liver directed therapy of pancreatic neuroendocrine tumor liver metastases. Dr. Ziv will evaluate whether the molecular biomarker, DAXX mutation, is a predictor of poor response to liver-directed therapy. This work has the potential to identify which patients will most likely benefit from treatment and to provide insight into why patients may or may not respond to treatment.

IPSEN is proud to sponsor the continuation of Edda’s work on behalf of NET patients through this Clinical Investigator Scholarship. IPSEN Biopharmaceuticals supports this research scholarship in the form of a $100,000 grant directed to NANETS to administer over the course of the two year grant period. The NANETS Research Committee establishes the award criteria, reviews process, and independently selects the recipient.

Memorial Sloan Kettering Cancer Center
BTSI Grant

NANETS congratulates Brian Untch, MD of Memorial Sloan Kettering Cancer Center as the NANETS 2017 Basic Translational Science Investigator (BTSI) Award recipient.

Dr. Untch proposed to explore new approaches for treating neuroendocrine cancers. The award will fund Dr. Untch’s work assessing the effectiveness of peptide receptor radionuclide therapy (PRRT), which targets somatostatin receptors in mouse models of neuroendocrine cancer. Somatostatin receptor ligands such as DOTA-TATE have been established as effective tools for detection of neuroendocrine tumors such as those found in pancreatic and gut cancers. However, these detection agents are now also being considered for their potential as treatments. This new field of “theragnostics” holds promise as an approach that may be combined with other classes of drugs to more effectively treat neuroendocrine cancers. Indeed, Dr. Untch’s research includes assessing the combined effects of PRRT and other promising chemotherapeutic approaches. The potential of these studies to have an impact on neuroendocrine cancer treatment, together with the strength of Dr. Untch’s investigator/mentor team and institution, convinced NANETS that this was the project to support with this year’s award.

The BTSI is sponsored by the Neuroendocrine Tumor Research Foundation (NETRF) and is made possible by the generous support of the Margie and Robert Peterson Foundation. The BTSI is awarded to a NANETS member in their first five years of faculty appointment and is meant to encourage the pursuit of basic or translational research with a focus on neuroendocrine tumors. The BTSI is a grant award of $100,000 to be distributed over the two year grant award cycle.